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Further clinical trials are needed to validate these strategies effectiveness and establish standardized protocols for incorporating antioxidants into IBD treatment regimens

Naltrexone-bupropion combination : This acts centrally to reduce appetite but has limited evidence in IBD populations

The authors also thank Michael V Sofroniew (University of California Los Angeles) for providing the GFAP-Cre mice, and Shigeyoshi Itohara for providing CaMKII-Cre mice