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Third, the optimal positioning and sequencing of GLP-1-based therapies relative to resmetirom and other emerging MASH agents (e.g., lanifibranor, pegozafermin, semaglutide combination regimens) requires dedicated combination trials, of which preliminary data from the MAESTRO-NASH secondary analysis are encouraging

Read clinical review Evidence-based guide to semaglutide (Ozempic) dosing considerations for East Asian patients, including pharmacogenomic factors, lower BMI thresholds, and clinical trial subgroup data

Fizzah Iftikhar, orcid.org/0009-0006-9380-632X