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Medical weight loss may be appropriate for adults who: Have a BMI of 30 or higher Have a BMI of 27 or higher with weight-related health conditions Struggle to lose weight through diet and exercise alone Want physician-supervised treatment Need help controlling cravings and hunger The most successful programs combine medication with: Nutritional guidance Physical activity Lifestyle coaching Ongoing monitoring Cost Considerations: Semaglutide vs Tirzepatide Cost can significantly influence treatment decisions

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doi: 10.1001/jama.2016.1252