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Additionally, developing intravitreal nanocarriers loaded with ferroptosis inhibitors could provide sustained retinal drug delivery, addressing the chronic nature of DR (101)

These symptoms occur because excess glutathione can increase glutamate levels (an excitatory neurotransmitter)

Amsterdam, The Netherlands: 2014

Metabolic Concerns TMAO (Trimethylamine N-Oxide) Production: Recent concern (2025): Approximately 90% of oral ALC metabolized to TMAO by gut microbiota[21] Plasma TMAO levels: Can reach 50 M after supplementation (1.5 g dose)[21] Cardiovascular risk: Elevated TMAO previously associated with adverse cardiovascular outcomes in observational studies Clinical significance: Uncertain