Some of the more common categories include: Acetaminophen (Tylenol) one of the most well-known for depleting glutathione, especially with frequent use or higher doses Antibiotics can increase oxidative stress and disrupt the gut microbiome, which indirectly impacts glutathione status Statins may increase oxidative stress in some individuals and impact mitochondrial function Chemotherapy drugs significantly increase oxidative stress, rapidly using up glutathione Certain psychiatric medications can increase oxidative load depending on the medication and individual response This does not mean these medications should be avoided if they are needed.But it does highlight the importance of supporting the body during and after use , especially when it comes to detoxification, nutrient status, and overall resilience
The underlying pathophysiology of this early worsening is believed to involve hemodynamic shifts in a retinal microvasculature that has lost its capacity for autoregulation
J Leukoc Biol 52:135142 Blomberg OS, Spagnuolo L, Garner H, Voorwerk L, Isaeva OI, van Dyk E, Bakker N, Chalabi M, Klaver C, Duijst M et al (2023) IL-5-producing CD4(+) T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer
The answer depends on why you are deficient