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These experiments were then repeated using 120-fold more input protein for the binding to streptavidin agarose and subsequent elution and separation by SDS-PAGE

It is widely known that matrix metalloproteinase-9 is responsible for breaking down the extracellular matrix and promoting the movement of RPE cells to Bruchs membrane, which in turn plays a role in the development of AMD

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Simental-Menda et al