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[] According to the same report, LA was also found to be most effective in chelating Cu 2+ , Zn 2+ and Pb 2+ , but instead was incapable of chelating Fe 3+ , while on the hand, DHLA will form complexes with Cu 2+ , Zn 2+ , Pb 2+ , Hg 2+ and Fe 2+ which are known to be poorly soluble in water

These results imply two different but potentially overlapping interpretations

7,8,9,10 Additionally, changes in cellular metabolism, induced by signals from various pathways, affect cell function and fate in response to different pathological conditions

TUNEL assay Apoptosis of NPCs was measured by TUNEL assay kit- BrdU-Red (abcam ab66110), according to the manufacturers protocol