Pharmaceutical preparation: Each 30 mL vial contains: 100 mg of vitamin B1 in form of thiamine hydrochloride, 2 mg of vitamin B2 in form riboflavin-5-Phosphate Sodium, 100 mg of B3 in form niacinamide, 2 mg of vitamin B5 in form of dexpanthenol and 2 mg of vitamin B6 in form of pyridoxine hydrochloride
However, preclinical studies demonstrate therapeutic effects with once-daily or even less frequent administration, suggesting tissue distribution, receptor binding, or cellular signaling effects extend beyond plasma clearance
There are several toxicity sites and lists where people became very ill on much lower doses -- in fact, B6 toxicity can come from doses lower than even 25 milligrams/day
With proper guidance and consistent treatment, they can significantly improve health, energy, and appearance