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Neither is universally "better." The right molecule depends on your BMI, metabolic markers, tolerance, budget, and long-term treatment goals a decision that belongs in a consultation room, not a comment section

While some studies found no difference between individuals with T2DM and matched non-diabetic controls ( per se and glycaemic control, since it is unclear whether changes in soluble DPP-4 activity in the circulation accurately reflect any changes in total DPP-4 activity

the British Medical Journal also argues that preserving muscle mass and physical function should also be a central goal of obesity treatment instead of focusing only on weight loss