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Some patients may require laboratory testing before treatment, while others may not

Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations (8.5)]

It is important to note that organelle-containing erythroid lineage cells can undergo intrinsic [37] and extrinsic apoptosis [38], receptor-interacting serine/threonine-protein kinase 1 (RIPK1)-dependent necroptosis [39], or iron-driven ferroptosis [40]

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