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By targeting three key metabolic pathways at once, it has become a major focus in modern metabolic and body-composition research

And while it varies by each person especially in those with cardiovascular or kidney disease the recommended amount of water to drink daily is 3.7 liters (125 ounces) for men and 2.7 liters (91 ounces) for women

Treatment selection should be individualized based on clinical priorities and patient characteristics

Clinical examination using a Woods lamp that emits black light (UVA1) and dermoscopy may be used to aid in diagnosis and determining the level of melanin deposition (Figures 1B and 1C)