Because it degrades in blood in a pathway involving amino-peptidases, it may not be suitable for people who take medications that inhibit or are metabolized by peptidases (e.g., captopril, a treatment for hypertension).4 Also, based on what we know about other therapeutic peptides, we would say DSIP is contraindicated for women who are pregnant or breastfeeding as well as people with a personal history of cancer
For a major biologic product, managing SPCs across 30 jurisdictions can cost several million euros annually in legal fees and administrative costs, a sum that is easily justified against the billions in revenue those SPCs protect
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Kahya, U., Kseer, A