[DOI] [PubMed] [Google Scholar] 133.Langlois A, Dal S, Vivot K, Mura C, Seyfritz E, Bietiger W, Dollinger C, Peronet C, Maillard E, Pinget M, Jeandidier N, Sigrist S
Expanding the use of GLP-1 receptor agonists across obesity, cardiovascular disease, chronic kidney disease, MASH, and other metabolic disorders requires manufacturers to generate robust long-term clinical evidence for each therapeutic indication
Since the drug was undetectable in milk at all time points tested (0, 12, and 24 hours post-dose for semaglutide), there is no peak concentration period to avoid
Comparing GLP-1s with sodium-glucose cotransporter-2 (SGLT-2) inhibitors, they found the weight loss injections both reduced the risk of addiction in people with no previous history and reduced adverse outcomes and deaths in those who already had a diagnosed substance use disorder