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Aberrant activation of Drp1 disrupts mitochondrial homeostasis, thereby triggering NLRP3 inflammasome activation and caspase-3 cleavage, which in turn amplify neuroinflammatory cascades (Sbai et al., 2023)

Among them the most prominent ones are SQSTM1/p62, NDP52, next to BRCA1 gene 1 protein (NBR1), Tax1-binding protein 1 (TAX1BP1) or optineurin (OPTN)

Limitations of the study: The authors say that their use of the p-value within the study may limit the findings of the experimental process

This inflammation is usually the result of an infection by the H.pylori bacteria which gradually destroys the cells in your stomach lining if not treated