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Specifically, GLP-1RAs can suppress vascular smooth muscle cell (VSMC) proliferation and migration via the cAMP/PKA pathway in C57BL/6 mice [61]

Paunel Vukasinov, This paper adds to growing evidence that GLP-1 receptor agonists may have an oncologic impact by improving metabolic health. He noted that the findings should be interpreted cautiously, as the study was observational, but the results highlight the potential role of metabolic health in cancer outcomes

GLP-1 users may differ from nonusers in ways that are not fully captured, such as socioeconomic status, health behaviors, disease severity, medication adherence, or access to care." Lakkis notes that the study also did not report how much weight participants lost, making it difficult to determine how much of the benefit may have been driven by weight reduction itself

PCAB absent