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The body naturally produces GLP-1 in the intestines in response to food intake, and this plays a key role in regulating appetite and blood glucose levels and improving satiety (the feeling of fullness after eating)
Another study evaluated the effects of rilonacept in the non-obese diabetic mouse model for IL-1 inhibition therapy and found that, compared to anti-CD3 therapy alone, rilonacept did not provide additional benefits in reversing the onset of diabetes [330]
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