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Among the 4 patients who developed thyroid dysfunction in the Abs-negative group, two had a positive anti-thyroid antibody status at thyroid dysfunction onset (positive TgAb and TPOAb in one and positive TgAb in the other patient), suggesting the involvement of thyroid autoimmunity even in patients negative for anti-thyroid antibodies at baseline

Additionally, we maintain comprehensive documentation of our manufacturing practices and protocols, which are designed to meet or exceed regulatory standards

Silva AC, dos Santos AGR, Pieretti JC, Rolim WR, Seabra AB, vila DS

most events were mild, and none was considered serious or resulted in discontinuation