Acetazolamide usage has been associated with memory impairment, and many investigations have shown deficits in language, working memory, verbal fluency, intelligence quotient, and verbal learning
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In preclinical models of NASH, the administration of AC3174, an analogue of exenatide, led to significant reductions in body weight, LFC, and levels of plasma alanine aminotransferase (ALT) and triglyceride [24]
As observed in other insulin-resistant mouse models, this increase in cell mass is likely to act as a compensatory mechanism to counteract the insulin resistance in SKO mice