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Semaglutide's Clinical Development and Approval Timeline Semaglutide was originally developed as a diabetes treatment and approved by the FDA in 2017 under the brand name Ozempic

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Consequently, a phase 3 trial on ambroxol has been planned and is due to start recruitment in the near future (NCT05778617), a phase 2 trial in GBA-associated PD is ongoing (NCT05287503) [124], and another phase 2 trial on PD dementia is expected to finish in December 2025 (NCT02914366) [125]

Conclusion In recent years, researchers have gradually appreciated and revealed the potential role of ferroptosis in endometriosis