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Meta-analyses using data from randomized, controlled CV outcomes trials showed that GLP-1 RAs were associated with a significant reduction in the risk of three-component major adverse CV events (CV death, non-fatal myocardial infarction and non-fatal stroke), and a significant reduction in the risk of fatal or non-fatal stroke, versus placebo in addition to standard-of-care (SoC) treatment [13, 14]

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Most patients notice reduced hunger and increased fullness within 37 days of their first injection, though the appetite-suppressing effect builds over 46 weeks as your dose increases

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GLP-1 Effects on BMI & Body Weight What Research Shows GLP-1 receptor agonists have been studied extensively, and the results are very consistent

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