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(3) Safety issues should be addressed before clinical translation

The pharmacology of the medication is that it slows your gut motility down so much that you hold on to stomach contents a lot longer

In cases where elevated CBS or CSE expression occur, use of specific inhibitors for these enzymes may be beneficial as in the case of Down syndrome, where trisomy of chromosome 21, where Cbs is located, causes excess H 2 S production (Kamoun et al ., 2003)

The uptake of the imaging agent was correlated with the number of CD68-positive macrophages in the infarcted area and -smooth muscle actin staining in the distal myocardium