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And they act on the hypothalamus and brainstem to reduce the reward value of food, a subtle but profound shift that many patients describe as simply not thinking about food the way they used to

Compared to healthy individuals, IBD patients exhibit universally reduced levels of the microbially derived aryl hydrocarbon receptor (AhR), which may also exert effects by inhibiting the NF-B/p65 signaling pathway (85)

In addition, the activity of specific enzymes can be measured in lymphocytes or in skin fibroblasts, as these cell types express all lcFAO enzymes [5]

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