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Similar to other benign lesions, once the melanoacanthoma is diagnosed, the site is usually just monitored, as these lesions are highly likely to regress within 2 to 6 months after biopsy (65, 66)

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It should be mentioned that some hormones (or their metabolites), especially sex hormones, i.e., androgens, estrogens, and progesterone, but also glucocorticoids, when occurring in environment in amounts exceeding these that are safe for health, may also serve as EDCs [6]