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Proinflammatory cytokines, such as tumor necrosis factor-alpha (TNF-), interleukin-1 beta, and interferon-gamma (IFN-), promote ROS production, while ROS scavengers such as pyrrolidine dithiocarbamate and N-acetyl-cysteine (NAC) can reduce the ROS levels induced by these cytokines 14

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Compounded semaglutide expiration varies by pharmacy but is usually 30 to 90 days from the compounding date when stored properly

The SURMOUNT-4 trial demonstrated 25.3% total body weight loss over 88 weeks in the treatment continuation group