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(Dai et al., 2009) have revealed that in vivo massive estrogen exposure promotes inflammatory responses that include enhanced secretion of Th1 related cytokines (IFN, IL-12, IL-1), inflammatory chemokines (MCP-1 and MCP-5), and induction of inducible nitric oxide synthase (iNOS) and cyclooxygenases-2 (Cox-2), leading to the liver damage

The simple truth is that environmental factors accelerate aging and impact cellular health

The same fundamental principles apply: gentle handling, correct diluent, proper storage