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Microglia-derived IL-1 can self-activate toll-like receptor 4 (TLR4), thereby reducing presynaptic GABA synthesis, and can activate protein kinase C (PKC) in neurons to suppress postsynaptic GABA receptor activity (180)

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modele in vivo nad orodkow aktywnoci melanokortyn (Wessells 2000) Farmakokinetyka i stabilno analogw -MSH wpyw modyfikacji Nle/D-Phe i cyklizacji na odporno na proteoliz i czas ptrwania

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