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A Phase 2 trial (a mid-stage human trial, typically involving a few hundred participants) published in the New England Journal of Medicine in 2023 reported an average weight loss of about 24% at 48 weeks with the highest dose

Despite the horror stories, some tell us the tan is worth the risk

"Esta es una poblacin de alto riesgo y, tradicionalmente, hemos contado con datos limitados para guiar las decisiones de tratamiento", argumenta Amy Sheer, profesora asociada de medicina y directora del programa de especializacin en medicina de la obesidad de la Universidad de Florida en Gainesville

In fact, for some, it looks even more prominent after weight loss