[00:30:41] Emily Field: In some cases, slowing the pace of dosage escalation or having a conversation about whether the current dose is appropriate, may better support the bigger goal, and the bigger goal, again, is not just rapid weight loss
Experimental studies in islet transplantation and thrombosis models demonstrate that BL exerts anti-ferroptotic effects through multiple mechanisms, including upregulation of HO-1/Nrf2 signaling, enhancement of cellular viability, elevation of antioxidant capacity, and reduction of cell death (Yao et al., 2020a,b)
The consensus among diabetes specialists and GPs is that Mounjaro should be used as part of a comprehensive diabetes management strategy that prioritises lifestyle modificationsincluding a balanced diet, regular physical activity, and weight managementalongside pharmacological treatment
This process encourages new collagen and elastin production, which helps restore firmness, elasticity, and an overall smoother complexion