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Classical Nrf2 Transcriptional Targets It is clear that Nrf2, once released from Keap1 binding, is able to maintain the redox homeostasis and to promote cell survival by activating the transcription of its multiple cytoprotective target genes containing antioxidant response elements (ARE) in their promoters (Figure 2)

In this study, an extensive mapping of peripheral blood cells of patients which suffered from type 1 diabetes revealed the expression of parameters related to aging and associated with PD-1 expression in memory T-cells

Schizophrenia Schizophrenia is characterized by psychotic symptoms and cognitive impairments

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