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Description

They have been reported to reduce symptoms of angina and peripheral vascular disease, and they may improve outcomes for people with serious heart conditions, such as coronary heart disease or heart failure [5]

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Elevated expression of IGF-IR in BCR/ABL + cells may promote the development and self-renewal of chronic myeloid leukemia, while downregulation of IGF-IR in BCR/ABL + cells leads to acute lymphoblastic leukemia (ALL) [14]

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