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This proton pumping creates a proton-motive force consisting of electrical and proton gradients

This regulation prevents ROS-induced damage to cellular structures, such as lipids, proteins, and DNA, which is pivotal in mitigating diabetes complications like nephropathy and neuropathy

Abstract Erectile dysfunction (ED) is a prevalent condition affecting mens sexual health, with oxidative stress (OS) having recently been identified as a significant contributing causative factor

Despite the preclinical promise shown by pharmacological agents that target ferroptosis-such as inducers like erastin and RSL3, and inhibitors like fer-1-their application in clinical settings encounters difficulties, which include unintended effects and restricted tissue specificity [2, 99]