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The American Diabetes Association Standards of Care emphasizes the importance of resistance training and adequate protein intake during pharmacologic weight loss to maintain muscle mass, and creatine supplementation may support these goals

It appears to work best on stubborn subcutaneous fat that resists diet and exercisethink love handles and lower belly

It is also prescribed for weight management in individuals who are overweight or have obesity

Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS-CVOT design and baseline characteristics