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By employing tumour -specific targeting, controlled release mechanisms, and multifunctional designs, these systems offer a pathway to balance the dual roles of oxidative stress in cancer progression and treatment

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GSTs are able to conjugate glutathione (-l-glutamyl-l-cysteinyl-glycine, GSH) to a wide range of hydrophobic and electrophilic molecules including many carcinogens, therapeutic drugs, and many products of oxidative metabolism, making them less toxic and predisposed to further modification for discharge from the cell (Fig

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