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Holly Lofton, director of the Medical Weight Management Program at NYU Langone

The stomach, adipose tissue, bone, and pancreas all express GIP receptors, and these have also been found in the cerebral cortex, hippocampus, and olfactory bulb, among other parts of the brain [15, 16]

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Clinical studies have found these medications may: Improve insulin sensitivity Support healthier blood sugar regulation Improve certain cardiovascular risk factors Reduce inflammatory signaling Improve lipid profiles in some patients Researchers continue to investigate whether some of these benefits may occur independently of weight loss, although many questions remain about how these medications should be used outside their approved indications