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When activated, GLP-1 receptors trigger a cascade that slows stomach emptying, lengthens the time food takes to leave the gut, boosts insulin release in response to glucose, and reduces appetite signals in the hypothalamus

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Clin Cancer Res 24:334340 Campbell JD, Alexandrov A, Kim J, Wala J, Berger AH, Pedamallu CS, Shukla SA, Guo G, Brooks AN, Murray BA, Imielinski M, Hu X, Ling S, Akbani R, Rosenberg M, Cibulskis C, Ramachandran A, Collisson EA, Kwiatkowski DJ, Lawrence MS, Weinstein JN, Verhaak RG, Wu CJ, Hammerman PS, Cherniack AD, Getz G, Cancer Genome Atlas Research Network, Artyomov MN, Schreiber R, Govindan R, Meyerson M (2016) Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

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