Chemical Class: Synthetic heptapeptide analog of -MSH (melanocortin peptide) IUPAC Name (peptide form): Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH Peptide Sequence (cyclic): Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH (Cyclized through AspLys side-chain lactam bridge) Molecular Formula: CHNO Molecular Weight: 1025.2 g/mol Structural Features: Heptapeptide N-terminal acetylation Side-chain lactam (AspLys) macrocycle Contains non-canonical amino acids: Nle (norleucine) and D-Phe Designed for high affinity and selectivity toward MC3R and MC4R receptors This product is intended solely for laboratory research purposes
S., Kalveram, B., Raasi, S., Groettrup, M
At the end of the treatment period, patients from both groups showed significant reductions in both the neuropathy symptom score and neuropathy disability score, with no meaningful difference between the two groups
September 2023: FDA placed multiple peptides including CJC-1295 (free base, acetate, DAC variants) and ipamorelin (acetate and free base) on Category 2 of the interim 503A bulks list, signaling significant safety or evidence concerns and effectively halting routine 503A compounding
