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Description

Combined inhibition of glycolysis and AMPK induces synergistic breast cancer cell killing

The SURMOUNT-1 trial, which followed participants for 72 weeks, demonstrated that patients on the highest dose (15 mg) achieved an average weight loss of 20.9% from baseline, with weight loss continuing throughout most of the study period before stabilizing

Bourbouloux, A., Shahi, P., Chakladar, A., Delrot, S