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177Lu-PSMA-617 gained FDA approval in 2023 for patients with PSMA-positive mCRPC after progression on ARi and taxane-based chemotherapy, following the phase III VISION trial demonstrating that the combination of 177Lu-PSMA-617 with best standard-of-care (BSoC) therapy improved median overall survival and radiographic progression-free survival compared to BSoC alone (NCT03511664) 83

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Mutagenicity tests performed in Salmonella typhimurium, Saccharomyces cerevisiae, and Schizosaccharomyces pombe indicate that levocarnitine is not mutagenic

Biosimilars are biologic drugs that are highly similar to an existing biologic that is already on the market (e.g