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Some patients want to come into the office and have a nurse give them their injections, while others are comfortable doing it themselves at home

Still, the strength of Mounjaro and Zepbound remains impressive, and investors have taken notice

Rodent models including Sprague Dawley, Wistar and rarely Albinos/LEW CrlCrlj rats, as well as C57BL/6 mice and New Zealand rabbits, remain preferential for in vivo research

Several studies have reported that supplementing rats with both L-carnitine and alpha-lipoic acid halts age-related increases in reactive oxygen species (ROS), lipid peroxidation, protein carbonylation, and DNA strand breaks in heart, skeletal muscle and brain, concomitant with improvement in mitochondrial enzyme and respiratory chain activities [146149]