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They also are sensitive to environmental conditions and can change chemical composition if stored at the wrong temperatures or shaken too vigorously, increasing the risk of an immune response or decreasing their effectiveness

Published research protocols use administration frequencies ranging from daily to three-times-weekly depending on study objectives, with intermittent dosing often producing comparable or superior results to daily administration in long-term neuroplasticity studies

They will also inform you about the possible side effects and expected results including the need for maintenance

most evidence remains preclinical