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In practice, individual results vary based on starting weight, adherence to lifestyle recommendations, individual metabolic factors, and the comprehensiveness of supportive care

If you want a detailed breakdown of what the initial period looks like, our guide on when you start losing weight on semaglutide covers the realistic timeline

Semaglutide starts at 0.25 mg weekly for four weeks before stepping to 0.5 mg, then escalates in 4- to 8-week intervals toward 2.4 mg [3]

70 Potentially Higher Intakes: For athletes or individuals in significant energy deficits, recommendations can range even higher, sometimes up to 2.0-2.4 g/kg/day