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Description

Knockdown of TGF-RII in gastric organoids with co-occurring CDH1 (encodes protein E-cadherin) and TP53 mutations induces features of metastatic diffuse gastric cancer, including severe dysplasia, focal invasion, and robust in vivo tumorigenicity

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Besides genetic predisposition, the development of DPN is closely linked to diabetes control and the effectiveness of its treatment, particularly in the early years following diagnosis [16]