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The GSH/GSSG redox potential has become a fashionable electrochemical parameter believed to be a major driving force of redox reactions regulating biological events (Schafer and Buettner, The impact of glutathione on biological redox events Whoever tried to directly determine redox potentials of proteins electrochemically will not forget the boring minutes or hours of waiting until the needle of the potentiometer had come to rest

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Kumar et al., 2009) characterized by polydipsia (increased thirst), polyuria (frequent urination), and polyphagia (increased hunger) with consequences of homeostasis disruption because of impaired glucose metabolism