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Ozempic, Wegovy, and Zepbound have become popular for their ability to manage blood sugar levels and for their impressive weight-loss benefits

Contrave (naltrexone and bupropion) : In a study, Contrave resulted in a modest weight loss of approximately 5 to 10% of body weight over a period of about a year

Additional clinical trials are required to evaluate the efficacy, safety, and tolerability of the different GLP-1s for disease management and for reducing cause-specific and all-cause mortality

Srdanovic S, orsteinsson H, Fririksson , Ptursson S, Maier VH, Karlsson K (2017) Transient knock-down of kcna2 reduces sleep in larval zebrafish