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But they add to the evidence that the antibiotic is linked to increased risk for QT-interval prolongation, which can cause an irregular heartbeat and increase the risk of sudden cardiac death in certain at-risk populations

[PubMed Central ID: PMC2222712]

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These melanogenesis studies have used MT-II as a high-potency reference agonist for establishing the upper limits of pharmacologically achievable melanogenesis through MC1R activation