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A randomized trial of the n-methyl-d-aspartate receptor glycine site antagonist prodrug 4-chlorokynurenine in treatment-resistant depression

57 In the United States, Australia and New Zealand, a more conservative measurement has been established, starting at a 4-hour APAP concentration of 150 g/mL and known as the treatment line, which is intentionally set lower to account for inaccuracies in the history of APAP ingestion and inherent laboratory error in APAP measurement

Mukha et al

For best results, start these 4-6 weeks before your challenging season to ensure that your foundation is strong. Research References Maintz L, Novak N