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Among the concerns about these medications, they found their association with an increased risk of suffering cholangiocarcinoma (hazard ratio (HR) 1.77, 95 % CI 1.043.01) [70]

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Activation of guanylate cyclase, increasing cGMP Answer =C Norepinephrine activates 1 adrenergic receptors by activating the Gs subunit of the G-protein complex which activates adenylate cyclase

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