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The effect of vitamin D supplementation on knee osteoarthritis, the VIDEO study: a randomised controlled trial

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Adequate protein intake (approximately 1.01.5 g/kg daily) supports collagen synthesis, whilst ensuring sufficient vitamin C, zinc, copper, and hydration (68 cups fluid daily) maintains dermal integrity during weight loss

demonstrated that oxidative stress and H 2 O 2 treatment led to a marked increase in senescence-associated -galactosidase activity but only to minimal apoptotic cell death in CSCs, suggesting that ROS triggered the induction of senescence and exhibited therapeutic potential in the eradication of drug-resistant CSCs [8]