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Dose Most clinical trials showing meaningful outcomes used 1,0001,500mg of berberine daily, split across two to three doses

Stabilization of blood sugar can make big differences in long-term health for patients with diabetes, [which is] a chronic disease that requires lifelong management. If GLP-1 becomes increasingly difficult to acquire, due to both financial and availability issues, it is difficult to predict how those dependent on the drug will fill the void

In many cases, a simple foundation built around multivitamin support, protein intake, hydration, and electrolytes is enough to support more consistent daily balance

doi: 10.1080/14728222.2020.1724285 37