A post hoc analysis of the REMODEL trial, presented by David Cherney, MD, PhD, and colleagues at the International Society of Nephrology World Congress of Nephrology in Yokohama, Japan, assessed the kidney-protective effects of semaglutide 1.0 mg among adults with type 2 diabetes (n=71), stratified by SGLT2 inhibitor use
16 studies looked only at over-weight or obese patients with no specific comorbidities
Rather than relying on external measures or strict calorie counting, individuals learn to recognize and respond to natural satiety signals, developing a healthier relationship with food that supports long-term weight maintenance
In summary, the SELECT trial provides evidence suggesting that semaglutide, a long-acting GLP-1 receptor agonist, could have broad applicability in the secondary prevention of cardiovascular events, thereby holding significant potential for public health impact